Refractive power and blood glucose changes: Studies in alloxan-induced and insulin-treated diabetic rabbits
| dc.contributor.author | Okorie, M. E. | |
| dc.contributor.author | Nweke, I. N. | |
| dc.contributor.author | Ahuama, O. C. | |
| dc.contributor.author | Azuamah, Y. C. | |
| dc.contributor.author | Unekwe, P. C. | |
| dc.date.accessioned | 2026-06-04T10:43:57Z | |
| dc.date.available | 2026-06-04T10:43:57Z | |
| dc.date.issued | 2015 | |
| dc.description | This article contains tables and figures | |
| dc.description.abstract | This study was carried out to determine the refractive power and blood glucose changes in alloxan-induced and insulin-treated diabetic rabbits. Eighteen healthy Dutch rabbits of both sexes weighing between 1.1kg and 1.9kg were used for this study. A 5% solution of alloxan monohydrate was administered intravenously to create a diabetic state. Refraction and blood glucose measurement was measured at approximately 5 days interval for 15 days before and after induction of diabetes by Streak retinoscopy. Results show a significant increase in hyperopia from + 1.49 D (+/- 0.59) to + 2.00 D (+/- 0.52) with increased blood glucose level after induction of diabetes. There was a significant positive correlation (P = 0.01) between hyperglycemic and hyperopic changes in the diabetic rabbits (r = +0.913, P<0.05). On the other hand, there was no significant correlation between insulin-induced blood glucose and refractive changes in insulin treated diabetic rabbits (r = +0.31, P > 0.05). | |
| dc.identifier.citation | Okorie, M. E., Nweke, I. N., Ahuama, O. C., Azuamah, Y. C. & Unekwe, P. C. (2015). Refractive power and blood glucose changes: Studies in alloxan-induced and insulin-treated diabetic rabbits. International Journal of Research 2(3), 728-736 | |
| dc.identifier.issn | e-2348-6848 | |
| dc.identifier.issn | p-2348-795X | |
| dc.identifier.uri | http://internationaljournalofresearch.org/ | |
| dc.identifier.uri | https://repository.futo.edu.ng/handle/20.500.14562/2804 | |
| dc.language.iso | en | |
| dc.publisher | U. P. | |
| dc.rights | Attribution-NonCommercial-ShareAlike 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-sa/4.0/ | |
| dc.subject | Refractive power | |
| dc.subject | blood glucose | |
| dc.subject | diabetes | |
| dc.subject | insulin | |
| dc.subject | hyperopia | |
| dc.subject | Department of Optometry | |
| dc.title | Refractive power and blood glucose changes: Studies in alloxan-induced and insulin-treated diabetic rabbits | |
| dc.type | Article |