Welcome to FUTOSpace
FUTOSpace is the Federal University of Technology, Owerri open-access repository that collects, preserves and make available in digital format the intellectual output of the university's community:
Communities in FUTOSpace
Select a community to browse its collections.
- This community features addresses and speeches delivered by the University management and other official visitors to FUTO
- A community of media or content used to convey information about an event organized at the university
- This community features books, book chapters and books published by faculty members in the university
- This Community features the proceedings of conferences, seminars and workshops hosted by the FUTO or other bodies but had staff from FUTO attending and making presentations
- This community features research articles from FUTO staff published in journals hosted by FUTO
- A community of series of scholarly public lectures designed to commemorate a faculty member's appointment to a professorship
- Scholarly resources with relevant discussion points for use by faculty as teaching lectures, student reading content, and study guides
- A community of printed document containing information about activities in FUTO
- A community of series of lectures aimed at educating FUTO staff and the public about a specific area of study
- A community of question(s) administered to FUTO students in an examination
- Published Research Outputs
- Theses and dissertations by students and staff from all the Schools in FUTO
Recent Submissions
Comparative analysis of the antibacterial effects of emilia sonchifolia (tassel flower) and selected antibiotics on ocular bacteria, in vitro
(U. P., 2021) Ugwoke, G. I.; Ikoro, N. C.; Esenwah, E. C.; Azuamah, Y. C.; Megwas, A. U.; Nwakamma, G. I.; Ibe, C. N.; Ogbonna, U. C.; Umunnakwe, O. L.
Developments of bacterial resistance to available antibiotics have necessitated the screening of medicinal plants for bioactive compounds which is gaining increasing popularity in the world. Emilia sonchifolia (Emilia s.) is a multipurpose plant that has exhibited antimicrobial effects against a wide range of microorganisms. The antibacterial activity of Emilia s. (tassel flower) extracts were compared with selected antibiotics against ocular bacteria (Staphylococcus aureus, Pseudomonas aeruginosa and Neisseria gonorrhoeae) in vitro using the Kirby-Bauer disc diffusion method. Phytochemical screening of the plant in Ethanol, Methanol and Aqueous solvents showed the presence of Saponin, Tannin, Flavonoid, Phenol, Alkaloid, Steroid and Glycoside in all the extracts but Flavonoid was not present in the Aqueous extract. Bacteria used were isolated from the eyes of infected patients that visited the Federal University of Technology, Optometry Teaching Clinic and St Joseph’s Eye Hospital Mgbirichi all in Owerri, Imo State, Nigeria and were identified and characterized macroscopically using standard laboratory methods. Diameter of zones of inhibition was measured for the different extracts of tassel flower and selected antibiotics. The data collected were tabulated and analyzed using Paired T-test and one-way ANOVA at 95% confidence interval and at a 0.05 level of significance. Results showed that aqueous, ethanol and methanol extracts exhibited antibacterial activity against the isolates with mean diameter of inhibition zone 13.33±2.89, 9.33±1.16 and 7.67±2.52 respectively. Their effect on the isolates was significant with p(0.01) <0.05 while that of the antibiotics were 12.00±3.46 for gentamicin, 17.00±10.58 for ofloxacin and 5.00±0.00 for erythromycin. A Comparison of the effects of Emilia s. and antibiotics on the bacterial isolates using one-way ANOVA showed the effects of Emilia s. does not differ significantly from the antibiotics as p(0.58) >0.05. This shows that Emilia sonchifolia could become a promising natural antibacterial agent with potential application in pharmaceutical industries for the production of plantbased ocular drugs.
Design and evaluation of chronotherapeutic pulsatile drug delivery system of cilnidipine
(U. P., 2017) Nweje-Anyalowu, Paul C.; Anyalogbu, Ernest A. A.; Alalibo, White Jim
At present scenario the drug regimen based on circadian rhythm is recently gaining much attention worldwide by researchers. Justification behind it is that, there are various diseases like asthma, hypertension, and arthritis show circadian variation that demand time scheduled drug release for effective drug action. A chronodelivery system, based on biological rhythms, is a state-of the- art technology for drug delivery. The aim of present work is formulate and evaluate a press coated pulsatile release tablets of Cilnidipine using an admixture of hydrophilic polymer i.e. hydroxypropyl methyl cellulose (HPMC) and pH sensitive polymers (ethyl cellulose, eudragit S-100) in order to achieve a predetermined lag time for chronopharmacotherapy of Hypertension. Cilnidipine is the novel calcium antagonist accompanied with L-type and N-type calcium channel blocking function used for the treatment of hypertension. The tablets prepared were evaluated for different properties like bulk density, tapped density, Angle of repose and Carr’s index), hardness, thickness, weight variation, friability, drug content uniformity and in vitro drug release study.
A comprehensive review on the feasibility and challenges of millimeter wave in emerging 5G mobile communication
(U.P, 2019) Agubor,Cosmas Kemdirim; Akwukwuegbu, Isdore; Olubiwe, Mathew; Nosiri, Chikezie Onyebuchi; Ehinomen, Atimati; Olukunle, Akande Akinyinka; Okozi, Samuel Okechukwu; Ezema, Longinus; Okeke, Benjamin Chukwujekwu
This article presents a comprehensive review on the feasibility and challenges of millimeter wave in emerging fifth generation (5G) mobile communication. 5G, a multigigabit wireless network is the next generation wireless communication network. The mmWave cellular system which operates in the 30-300 GHz band has been proposed for use as the propagation channel. Its large bandwidth potential makes it a candidate for the next-generation wireless communication system which is believed to support data rates of multiple Gb/s. High frequency bands such as mmWave have channel impairments. These impairments are challenges that are necessary to be properly understood. Employing mmWave as a propagation channel requires dealing with these challenges which this paper is aimed at reviewing. One aim of the work is to discuss these challenges in a more elaborate manner using simple mathematical equations and graphics to ensure clarity. To achieve this, current related works were studied. Challenges and solutions are identified and discussed. Suggested research directions for future work are also presented. One is developing suitable electronic such as fast analog-to-digital (ADC) and digital-to-analog (DAC) systems necessary for the transmitter/receiver (TX/RX) system.
Sociodemographic factors influencing the uptake of rapid diagnostic test kits for the management of malaria among mothers of under five in a typical Nigerian population
(U. P., 2021) Dozie, U. W.; Ebirim, Chikere I. C; Nwobi, U. O.; Chukwuocha, U. M.; Ibe, S. N. O.; Dozie, I. N. S.
Globally, malaria constitutes a crucial public health challenge since it is the third major cause of death among children under the age of 5. Prompt and effectual malaria diagnosis is the major approach to the control and management of the disease. Objectives: The study investigated sociodemographic factors that influence the uptake of rapid diagnostic test (RDT) for malaria management among mothers of under 5. Method of Study: A descriptive cross-sectional design was used in the study in which 420 mothers of under 5 were randomly selected from five electoral wards in Owerri West L.G.A of Imo state. Structured questionnaire was used in data collection. Data were analyzed with SPSS statistical package (Version 21) in which Chi-square at 5% probability level was used to ascertain the association between sociodemographic and uptake of rapid diagnostic test (RDT). Results: Results showed that the mothers 161 (38%) were mostly in 30–49 years age bracket, were married (%). More than one-quarter of them was secondary school certificate holders who were civil servants who earn average monthly income of 10,000–17,000₦ 183 (44%). Less than half 180 (42.9%) of the mothers do test their child with RDT, particularly when their child has fever 103 (24.5%). Moreover, larger proportions 161 (89%) of this group know how to carry out RDT. Most of them indicated positive result of RDT to be double line on the strip 155 (86.1%). More than three-quarter of them 168 (93.3%) still use RDT even when they are aware that it involved finger prick of blood from the child. Majority of them 252 (60%) indicated that their custom/religion allows blood test when the child is ill. It was shown that the uptake of mRDT was more pronounced among mothers within the age group of 18–29 years (67.5%) (χ2 = 50.12; P < 0.001) who were single (75%) (χ2 = 74.77; P < 0.001). Uptake of mRDT was also highest (71.4%) among respondents who had tertiary education (χ2 = 91.35, P < 0.001) and are civil servants (57.1%) (χ2 = 65.80; P < 0.001) who earn average monthly income of 18,000 (68.8%) (χ2 = 34.65; P < 0.001). Within the communities, uptake of mRDT was
highest among mothers from Obinze compared to other communities with significant association (χ2 = 22.17; P < 0.001). Conclusion: Uptake will, however, be enhanced if the cost of RDT-based management is reduced. Enhancing the health education through media, conferences, seminars, and workshops using local dialects will also help in raising the knowledge and understanding of less or non-educated mothers on the benefits of RDT.
Soil enivironmental metals speciation and associated health risks in selected edible leafy plants on Amaechi and Four-Corner dumpsites in Enugu State, Nigeria
(U. P., 2014) Obasi, N. A.; Elom, S. O.; Edeogu, C. O.; Alisa, C. O.; Obasi, S. E.
This work evaluated environmental metals speciation and the associated health risks using fiveselected edible leafy plants in Amaéchi and Four-Corner dumpsites in Enugu, Enugu State,Nigeria. The soil and plants samples were obtained from Amaéchi and Four-Corner dumpsitesin Enugu and a nearby farm land (control site) and were subjected to standard methods ofchemical analysis. Results obtained showed that mean soil physicochemical parameters andtotal extractable metals were significantly higher (P < 0.05) in the dumpsites compared to controlsite. Carbon:Nitrogen (C:N) ratio was significantly higher (P < 0.05) in the control site compared to that in Amaéchi dumpsite. Sequential extraction showed higher percentages (%) of the nonresidual fraction for all the metals studied except Cu and Cr. The mean order of mobility and bioavailability of the metals were: Pb > Fe > Cd > Zn > Mn > Cr > Ni > Cu. Total mean concentrationof metals in roots, stems and leaves of Amaranthus hybridus, Talinum triangulare, Carica papaya,Ipomea batatas and Luffa aegyptica were significantly higher (P < 0.05) in the dumpsitescompared to control site. The translocation factor, biological concentration factor and biologicalaccumulation coefficient values of the plant species varied for all the metals. The health risks implications of the study were discussed.