Germicidal activities of some selected disinfectants on staphylococcus aureus and escherichia coli

dc.contributor.authorMgbemena, Ifeyinwa Celestina
dc.date.accessioned2025-03-27T13:06:34Z
dc.date.available2025-03-27T13:06:34Z
dc.date.issued2020-06-16
dc.descriptionA short research article with tables and figures.
dc.description.abstractThe germicidal efficacy of four common disinfectants used for different purposes was tested against two common pathogens namely Escherichia coli and Staphylococcus aureus. The disinfectants (Dettol, Jik, Izal and Purit) were diluted with sterile distilled water to achieve different concentrations (100%, 50%, 25%, 12.5% and 6.25%) and they were tested on the two organisms using Agar well diffusion method. The plates were allowed to incubate for 24 hours at 37℃.The germicidal efficiency of the disinfectants was evaluated by measuring the zone of inhibition of each disinfectant based on their varying concentrations. Dettol was observed to have the highest inhibition at 100% concentration and was more germicidal on E. coli than S. aureus with Minimal Inhibitory Concentration (MIC) value of 1:16 dilution against the two test organisms. This was closely followed by Jik which also showed more inhibitory activity against E. coli at the initial concentration recording the second highest inhibition rate compared to other disinfectants, but its efficacy decreased as the concentration dropped. Jik exhibited MIC value of 1:8 and 1:2 dilutions for Staphylococcus aureus and Escherichia coli respectively. Purit showed more inhibitory activity on S. aureus with 3.8mm zone of inhibition as against 1.3mm at 100% concentration, recording MIC value of 1:8 dilution on S. aureus and 1:16 dilution for E. coli. The disinfectant Izal was observed to be the lowest as it did not inhibit the growth of any of the organisms, indicating resistance of the organisms to the disinfectant at all concentrations. All the disinfectants apart from Izal inhibited the two test isolates. Only Dettol proved to be best among them. Therefore, Dettol is encouraged to be used in homes to prevent pathogenic infection.
dc.identifier.citationMgbemena, G. I. (2020). Germicidal activities of some selected disinfectants on staphylococcus aureus and escherichia coli. Journal of Microbiology & Biotechnology, 5(2), 000161
dc.identifier.doi10.23880/Ooajmb-1600161
dc.identifier.issn2576-7771
dc.identifier.urihttps://repository.futo.edu.ng/handle/20.500.14562/1717
dc.language.isoen
dc.publisherMedwin Publishers
dc.rightsAttribution-NonCommercial-ShareAlike 4.0 Internationalen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/
dc.subjectEpidermics
dc.subjectphenolics
dc.subjectIodophors
dc.subjectformaldhyde
dc.subjectglutaraldehyde
dc.subjectortho-phthalaldehyde
dc.subjecthydrogen peroxide
dc.subjectperacetic acid
dc.subjectsporostatic
dc.subjectDepartment of Biotechnology
dc.titleGermicidal activities of some selected disinfectants on staphylococcus aureus and escherichia coli
dc.typeArticle

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