Effects of M-health on medication adherence among people living with HIV and AIDS (PLWHA) and people with tuberculosis in Imo State
| dc.contributor.author | Ezelote, Judith Chinelo | |
| dc.date.accessioned | 2025-10-09T12:42:26Z | |
| dc.date.available | 2025-10-09T12:42:26Z | |
| dc.date.issued | 2025-04 | |
| dc.description | Doctoral thesis on medication adherence among people living with HIV and AIDS (PLWHA). It contains tables and diagrams | |
| dc.description.abstract | The study is on the effects of mobile health (m-Heath) on medication adherence among people living with HIV and AIDS (PLWHA) and people with tuberculosis in Imo State. Adherence is crucial in the management of HIV/AIDS and treating Tuberculosis to achieve the required treatment success rate. However, due to the longer treatment duration, adherence to Tuberculosis treatment is the most challenging factor affecting Tuberculosis control. Successful antiretroviral treatment is dependent on sustaining high rates of adherence among People Living With HIV/AIDS (PLWHA). This study assessed the effects of m-Health on medication adherence among PLWHA and people with tuberculosis receiving care at Federal University Teaching Hospital (FUTH) Owerri and Imo State Specialist Hospital Umuguma (ISSH). The study was guided with five objectives and five hypotheses. Quasi-experimental design was used. The study aimed to determine the level of adherence to prescribed medication dosing regimens and schedules, promptness in refilling prescriptions, and keeping appointments with health personnel among test and control groups using M-Health mplementation. It also assessed the percentage of people with tuberculosis who tested negative for sputum tests within 3 months of initiating treatment among the test and control groups. Instruments for data collection were the questionnaire and checklist. AIDS Clinical Trials Group (ACTG) as data collection instrument among PLWHA while the eight-item Morisky Medication Adherence Scale (MMAS-8) is used for people with tuberculosis. FUTH Owerri was randomly selected as the test group and ISSH Umuguma as the control group. Among 1740 and 3709 PLWHA receiving care at FUTH Owerri and ISSH Umuguma respectively, 223 at FUTH and 411 at ISSH Umuguma were non-adherent to their medication at the time of the study. Among 1401 and 1026 people with tuberculosis receiving care at FUTH Owerri and ISSH Umuguma respectively, 134 at FUTH and 128 at ISSH Umuguma were non-adherent to their medication at the time of the study. All the non-adherents were included in the study hence no sampling. The M-Health intervention was implemented only for the non-adherents in the test group. The results were analyzed using regression analysis with a p-value of ≤ 0.05. The results showed that both PLWHA and people with tuberculosis displayed improved medication adherence after the intervention compared to those in the control group. Among the 223 non-adherent PLWHA participants, 81.6% improved adherence to medication dosage, 76.8% to medication timing, 90% to refilling prescriptions, and 88.5% to attending doctor's appointments. This was in contrast to only 7%, 11.8%, 24%, and 18.2% improvement in the same categories among the control group. After the intervention and follow up, the treatment outcome for tuberculosis showed that 91.8% of the test group tested negative, while 95% of the control group still tested positive. Initially, the respondents had sub-optimal adherence levels, but the test group showed a statistical significant increase in adherence postintervention. This bidirectional SMS and phone call intervention improved adherence medication dosage regimen, time schedule, prompt refilling of drugs and attendance to clinic appointment among PLWHA in the test group while no significant difference was noted in the control group. Conclusion was drawn and it recommended incorporating m-Health as the standard care approach for people living with HIV/AIDS and tuberculosis to improve adherence to medication | |
| dc.identifier.citation | Ezelote, J. C. (2025). Effects of M-health on medication adherence among people living with HIV and AIDS (PLWHA) and people with tuberculosis in Imo State (Unpublished Doctoral Thesis). Federal University of Technology, Owerri, Nigeria. | |
| dc.identifier.uri | https://repository.futo.edu.ng/handle/20.500.14562/2220 | |
| dc.language.iso | en | |
| dc.publisher | Federal University of Technology, Owerri | |
| dc.rights | Attribution-NonCommercial-NoDerivatives 4.0 International | en |
| dc.rights.uri | http://creativecommons.org/licenses/by-nc-nd/4.0/ | |
| dc.subject | M-Health | |
| dc.subject | Adherence | |
| dc.subject | HIV/AIDS | |
| dc.subject | Tuberculosis. | |
| dc.title | Effects of M-health on medication adherence among people living with HIV and AIDS (PLWHA) and people with tuberculosis in Imo State | |
| dc.type | Doctoral Thesis |