Browsing by Author "Obasi, Kalu O"

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    Effect of dichlorvos on the fertility of adult male albino rats
    (Science Publication, 2015) Ezeji, Ethelbert Uchechukwu; Ogueri, Oluchi Dominica; Udebuani, Angela Chika; Okereke, Josephath N; Obasi, Kalu O
    Continuous use of pesticides could have adverse effects on the reproductive functions of humans and non-target organisms. This study was carried out to examine the effect of dichlorvos on the reproductive parameters of adult male albino rats. Twenty (20) adult male Wistar albino rats weighing between 130 – 225g were divided into 4 groups of 5 animals each. Three groups were given water contaminated with 0.01, 0.03 and 0.05% dichlorvos (DDVP) respectively. The control group was given distilled water without dichlorvos. All the animals were maintained on commercial animal feed (growers mash) throughout the period of the experiment which lasted for 28 days. There were significant reductions (p<0.05) in testosterone levels in rats exposed to dichlorvos. Testicular weight (testis and epididymis) and sperm count were significantly lowered in rats exposed to dichlorvos. Histological examination of the testes revealed levels of distortions in the cells of the seminiferous tubules as well as hypertrophy of the spermatogonia cells. These results show that dichlorvos has adverse effects in the reproductive functions of male albino rats.